Calming irritated peripheral nerves.
Perineural Injection Therapy (PIT) is a gentle, minimally invasive treatment designed to address pain arising from irritated peripheral nerves. It uses small injections of low-concentration dextrose placed just beneath the skin along the course of the affected nerve.
When a peripheral nerve becomes irritated, it can continue sending pain signals long after the original injury has healed. The goal of Perineural Injection Therapy is to calm these overactive nerves, reduce neurogenic inflammation, and create an environment that supports recovery.
Treatment begins with a comprehensive evaluation to determine whether a peripheral nerve is contributing to your symptoms. If appropriate, Perineural Injection Therapy offers a precise, drug-free approach to treating peripheral nerve pain.
Where Did It Come From?
Perineural Injection Therapy was developed by Dr. John Lyftogt of New Zealand after observing that low-concentration dextrose injections could significantly reduce pain associated with irritated peripheral nerves without the use of corticosteroids.
Today, PIT is practiced internationally as a conservative treatment for peripheral nerve pain.
How Does It Work?
Peripheral nerves carry signals between the brain, spinal cord, muscles, joints, and skin. When these nerves become irritated or compressed, they may continue sending pain signals and contribute to ongoing inflammation, tenderness, and altered movement.
Peripheral nerves rely on glucose as their primary source of energy. Current research suggests that low-concentration dextrose may help reduce neurogenic inflammation and support the normal function of irritated nerves.
What to Expect
Treatment consists of a series of small, shallow injections placed just beneath the skin along the affected peripheral nerve.
- Most patients feel immediate pain relief lasting from 4 hours to 4 days with overall steady imporovement.
- You are able to return to their normal daily activities the same day.
- Depending on the condition and your response to treatment, a series of treatments spaced several weeks apart may be recommended.
Is It Safe?
Perineural Injection Therapy has an excellent safety profile. Published clinical studies, including randomized controlled trials, have reported no serious adverse events associated with the low-concentration dextrose used in PIT.
The most common side effects are mild, temporary soreness or bruising at the injection sites.
Is Perineural Injection Therapy Right for You?
Not all pain originates from an irritated peripheral nerve. A comprehensive evaluation helps determine whether Perineural Injection Therapy is appropriate for your condition and whether it should be performed on its own or integrated with other treatments.
Our treatment recommendations are individualized and may incorporate Perineural Injection Therapy alongside electroacupuncture and naturopathic medicine to support your overall recovery.
If you've been living with persistent pain and conservative treatments have not provided lasting relief, a comprehensive evaluation can help determine whether peripheral nerve irritation is contributing to your symptoms.
Schedule a consultation to learn whether Perineural Injection Therapy may be appropriate for you.